Being creative does not necessarily make you a scientific inventor. Hence, this book could be a practical guide for anyone, including students, scientists, academia, and research institutions, to develop invention as well as a comfortable perception of science. This book is timely because invention is the key to compete in today's AI and robotic technology era. The author is a scientific inventor with 41 inventions, 30 of which are patented in the United States as of 2025, related to biotechnology, and biomedical, biomaterial, and microbial technology, as well as for food, environmental, and industrial application. He shares with the reader his knowledge-based scientific, technical skills and experiences for implementing different principles and mechanisms in various fields of science related to the invention process. The book also highlights motivations, inspirations, and types of culture as complementary factors for scientific invention. The book also contains a chapter about AI in relation to invention. In addition, the book presents the invention experience of people across the world and throughout history.