This work is unique among Sadra's writing in that it reworks and amplifies an earlier Persian work, the "Jawidannama". by Baba Afdal. The underlying theme of the work is the importance of self-knowledge in an individual's journey of origin and return.

Sadr al-Din Muhammad Shirazi (1572-1640), more commonly called Mulla Sadra was one of the grand scholars of later-period Islamic philosophy and has grown to become one of the best-known Muslim philosophers. "Iksir al-Arifin" or "Elixir of the Gnostics", is unique among Sadra's writings in that it reworks and amplifies an earlier Persian work, the "Jawidan-nama" ("Book of the Everlasting") by Afdal al-Din Kashani, or Baba Afdal. The underlying theme of Sadra's amplification is emblematic of Muslim philosophy: the importance of self-knowledge is an individual's journey of "Origin and Return", the soul's origins with God and its eventual return to Him. Everything, Sadra says, is on such a path, gradually disengaging from the material world and returning to a transdencent essence - all leading to a final fruition in which everything in the universe returns to God and finds permanent happiness. Philosophy, Sadra argues, is the most direct means to self-knowledge - and thus the best tool for navigating this journey.