Studies in the History and Culture of the Middle East are published as supplement to Der Islam founded in 1910 by Carl Heinrich Becker, an early practitioner of the modern study of Islam. Following Becker's lead, the mission of the series is the study of past societies of the Middle East, their belief systems, and their underlying social and economic relations, from the Iberian Peninsula to Central Asia, and from the Ukrainian steppes to the highlands of Yemen. Publications in the series draw on the philological groundwork generated by the literary tradition, but in their aim to cover the entire spectrum of the historically oriented humanities and social sciences, also utilize textual sources as well as archival, material, and archaeological evidence.

Beginning with volume 28, SME continues the series "Studien zur Geschichte und Kultur des islamischen Orients (STIO)".