Broad in scope and suitable for training programs in the successful application of proton therapy, this comprehensive volume is organized into two major parts. Beginning with an introduction and background to core concepts, the first section discusses physics and technology, clinical physics, neutron production, radiation biology, and treatment planning. The second part looks at specific clinical sites, including pediatric tumors, nervous system, prostate, lung, gastrointestinal, gynecological, head and neck, and sarcomas. Each chapter addresses clinical results, and treatment strategy. The final chapter presents proton therapy results in clinical trials.