“Global warming” and “climate change” have become common and trending subjects of interest in recent decades, due to their massive influence on biodiversity and the subsequent effects on sustainable uses by human beings. In recent times, various ecosystems have been severely inundated with issues that threaten the very survival of the biodiversity that we depend on. Biodiversity is highly essential, as our health, food, and economy all depend on it. Unfortunately, the rapid change in the Earth’s climatic and anthropogenic stressors are affecting all forms of life and non-life on earth, most such effects being irreversible. “Climate change and environmental perturbation: Impacts on biodiversity” highlights topics associated to the impacts of climate change and human-mediated environmental disturbances on biodiversity, as well as the use of micro-organisms in combating environmental pollution (including their potential as anti-biofouling agents).