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This book summarizes the recent advances for the understanding of circadian clock system in the regulation of drug metabolism and pharmacokinetics. Basic knowledge in the field of circadian clock and pharmacokinetics are systemically introduced to make it easier for readers to understand the entire book's contents. The rhythmic expression of DMEs (drug-metabolizing enzymes) and transporters are summarized, and the underlying mechanisms thereof (i.e., regulation by circadian oscillators) are discussed. Typically, evidence for the DME- and transporter-mediated chronopharmacokinetics, chronotoxicity and chronoefficacy are highlighted in this book.

Boekdetails

Formaat
Paperback / softback
Uitgever
Springer Verlag, Singapore
Imprint
Springer Verlag, Singapore
Auteur
Baojian Wu || Danyi Lu || Dong Dong, Springer Verlag, Singapore, Springer Verlag, Singapore
ISBN-13
9789811588099
Verschijningsdatum
2021-10-29
Editie
2020 ed.
Afmetingen
155 mm × 235 mm
Land van herkomst
NL

Paperback / softback

Circadian Pharmacokinetics

door Baojian Wu || Danyi Lu || Dong Dong

€ 187,74
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