Neurons in Action 2 is the second version of a unique software learning tool that combines hyperlinked text with NEURON simulations of laboratory experiments in neurophysiology. Version 2 features nine new tutorials introducing new channel types, single-channel simulations, and a redesigned interface. Neurons in Action's moving graphs provide insight into nerve function that is simply not possible with conventional, static text and figure presentations. Students discover how changing parameters such as neuronal geometry, ion concentrations, ion channel densities, and degree of myelination affect the generation of action potentials, synaptic potentials, and the spread or propagation of voltages within a neuron. For instructors, minimovies of NEURON simulations are provided for use in lectures.SYSTEM REQUIREMENTSWindowsWindows XP, Vista, 7, or 8Current version of FirefoxMacMac OS X 10.6-10.11